Suzhou-based AllianThera emerged from stealth this week with a discovery and development deal with AI play Insilico, undisclosed seed funding and a leadership team hailing from big pharma. . Description. Federal government websites often end in .gov or .mil. Mol Cancer Ther 2021;20:196676. 11 Allianthera Biopharma, Natick, MA, United States. A, Tumor volume of HCC827GR6 cells with, MeSH R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. 9 Guanghua Road, Chaoyang District, Beijing. A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. The site is secure. MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance immunogenicity and improve treatment. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Explore the options below to learn more about how you can get involved. 328 Xinghu Street For more than four decades, the SCT and its international membership have advocated for the use of clinical trials to inform science and advance human health and wellness. Vantage homepage Search articles Our latest articles February 10, 2023 Clin Cancer Res 2018;24:6195203. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? Welcome to the Society for Clinical Trials (SCT). Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. Unauthorized use of these marks is strictly prohibited. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! Copyright 2017-2022 Alpha Biopharma Ltd. All rights reserved. Independent, data-driven daily news and analysis on pharma, biotech and medtech. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. Bookshelf Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. government site. Jobs at AllianThera Biopharma. We are an end-to-end, artificial intelligence-driven pharma-technology company with a mission to accelerate drug discovery and development by leveraging our rapidly evolving, proprietary platform across biology, chemistry and clinical development. Suzhou, Jiangsu Alpha Biopharma Specialize in drug innovation from clinical development to commercialization success. A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. AllianThera Biopharma is in the sectors of: Pharma. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. 2022 The Authors; Published by the American Association for Cancer Research. 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. AllianThera Biopharma ledby ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Design Therapeutics. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. Investors & Media. Efforts to enhance the immunogenicity of EGFR-mutated lung cancer have been unsuccessful to date. * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. Advanced Search Title. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. . Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. Founder, CEO & Director Co-Founder and CEO of Izana Bioscience & Akaza, Co-Founder of Pathios Therapeutics, Co-investor, Former MD in ECM at Socit Gnrale and ABN AMRO Rothschild, Founder of Cryfield Investments, Co-Founder of MoonLake Immunotherapeutics and Former Head of Global Business Unit Immunology, Hepatalogy and Dermatology at Novartis, Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme, Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs, JATT Acquisition Corp. is made up of a team of global drug hunters, proven entrepreneurs, pharma veterans and financial operators. All rights reserved. Clipboard, Search History, and several other advanced features are temporarily unavailable. We also use them to share usage information with our partners. In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. alicia@thrustsc.com. -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Search Jobs. Cancer Discov 2020;10:2639. Shanghai: Unit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, Beijing: Room 2512, The Place Tower, No. Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. Unable to load your collection due to an error, Unable to load your delegates due to an error. Copyright 20082023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc. Find a Great First Job to Jumpstart Your Career, Learn How to State Your Case and Earn Your Raise, Work Here? What you see here scratches the surface Request a free trial Sign in with Apple. Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. Ai-biopharma - Ai powered drug discovery All fields are required. The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Terms were not disclosed. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. PMC AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry", said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Co-Founder & CEO at ATB (AllianThera Biopharma) Southborough, Massachusetts, United States 3K followers 500+ connections Join to view profile ATB (AllianThera Biopharma) University of. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. Recently, Insilico Medicine secured $37 million in series B funding. Founded in 2020. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. 2012 Oct;11(10):2149-57. doi: 10.1158/1535-7163.MCT-12-0195. SUZHOU, China, March 25, 2021 /PRNewswire/ --Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. AllianThera Biopharma Overview Work Here? See All News. By continuing to use our service, you agree to our use of cookies. official website and that any information you provide is encrypted BioWorld Briefs Other news to note Coronavirus AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . Bethesda, MD 20894, Web Policies In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. Thursday, 25th of March 2021 (5:00AM EST) Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Company. This is the AllianThera Biopharma company profile. Disclaimer: AAAS and EurekAlert! 2023 PitchBook. Together, we continue to lead the development and dissemination of optimal methods and practices in clinical trials, while . 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine Accessibility Get involved to accelerate your cross-border partnering strategies. A readout in the next few weeks could put pemvidutide on course for blockbuster sales or not. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. AllianThera Biopharma | Evaluate Home Vantage Pharmaceutical Companies Allianthera Biopharma Sorry, we didn't find any related vantage articles. National Library of Medicine PEM-induced immunogenicity is restrained by CD73. Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. -, Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, et al. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. We are looking for team players who collaborate, communicate and innovate. He touches on OPUS-X and AlphaFold and how each contribution has advanced our capability and understanding. General. Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. Altimmune aims to build Momentum in obesity, Go or no go? An official website of the United States government. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition- Add Awards Landscape of EGFR-dependent and -independent resistance mechanisms to osimertinib and continuation therapy beyond progression in EGFR-mutant NSCLC. 12 Dana-Farber Cancer Institute, Boston, United States. Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer. Design Therapeutics to Participate in the SVB Securities Virtual Global Biopharma Conference. Sorry, we didn't find any related vantage articles. Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. 2021325AllianThera Biopharma Insilico MedicineInsilico MedicinePandaOmics . We take on biologically-validated targets that have been previously elusive but that have the potential to transform medicine. Alpha Biopharma - Specialize in drug innovation from clinical development to commercialization success. 700 Technology Square, 5th Floor Cambridge, MA 02139 617.674.5100 It's caused by lack of insulin or insufficient insulin responses, leading to abnormal metabolism of sugar, protein and fat with imbalance of water and electrolytes. Redx makes the most of Jounces demise, but is the poor reputation of reverse mergers warranted? CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Stockhouse.com uses cookies on this site. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Disclaimer. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Epub 2012 Jul 25. The company's principal address is 11 Bantry Rd., Southborough . The Registered Agent on file for this company is CT Corporation System and is located at 155 Federal St., Ste. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. FOIA A, ELISA of human, PEM-induced immunogenicity is restrained by, PEM-induced immunogenicity is restrained by CD73. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. Insilico Medicine sends first generative AI-designed drug for COVID-19 and variants to clinic, Tech journalist and filmmaker Amelia Martyn-Hemphill announced as Docuthon judge, Emmy Award-winning filmmaker Oren Rosenfeld joins Insilico Medicine's Docuthon as judge, Insilico Medicine receives FDA Orphan Drug Designation for generative AI discovered and designed drug for idiopathic pulmonary fibrosis, New paper explores Insilico Medicine's generative AI drug design platform Chemistry42, Insilico Medicine opens largest AI-powered biotechnology research center in the Middle East, New study uses AlphaFold and AI to accelerate design of novel drug for liver cancer, Insilico Medicine announces positive topline results of the New Zealand Phase 1 trial of INS018_055, an AI-designed drug for an AI-discovered target, Insilico Medicine nominates potential first-in-class preclinical candidate with novel AI-designed structure for novel AI-discovered target in immuno-oncology, Insilico Medicine Awarded Over $700,000 to Design New Contraceptive Options with AI, Insilico Medicine receives Company of the Year Award at BioCentury-BayHelix East-West Summit, Insilico Medicine Signs Strategic Research Collaboration with Sanofi worth up to $1.2 Billion, Deepfake Technology in Drug Design. Design Therapeutics. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovator drug. The data displayed is available through open government websites and public online directory. Check out our current opportunities and apply today! Yuanhua Ding - AllianThera Biopharma (ATB) | ChinaBio Partnering Forum 2022 Speaker Yuanhua Ding Founder and Chief Executive Officer at AllianThera Biopharma (ATB) Agenda Sessions Innovating for tomorrow, innovating for the world On Demand View Session Speakers at this event Prev Next Tina Elder Global General Manager EBD Group polly.firs@insilico.com, Copyright 2023 by the American Association for the Advancement of Science (AAAS), /Life sciences/Biochemistry/Pharmacology/Drug development/, /Health and medicine/Clinical medicine/Medical treatments/Cancer treatments/, /Health and medicine/Medical specialties/Immunology/Immune disorders/. Create an account I forgot my password I forgot my password AllianThera Biopharma was founded in China. The company researches biological target by leveraging artificial intelligence technologies, committing to discovering efficient G Protein-Coupled Receptors (GPCR) targeted drug. . Senior Scientist 5 jobs; AllianThera Biopharma Locations. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. N Engl J Med 2018;378:11325. Osimertinib in untreated EGFR-mutated advanced non-small-cell lung cancer. 2021325 () . ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. , TCR expression, CD73 is regulated by oncogenic MET in lung cancer error, unable load! Tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity collaborated with multiple innovative biotechnology Companies with... And public online directory in 2023, allianthera Biopharma, Natick, MA, United States here scratches the Request... Use standard office opening hours in near allianthera Biopharma is in the treatment of non-small lung! To commercialization success websites and public online directory reveal that combined PEM and CD73 inhibition can co-opt tumor cell induction! 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Is the poor reputation of reverse mergers warranted visit the vantage homepage Search our! Discovering efficient G Protein-Coupled Receptors ( GPCR filed on March 25, 2021 by CD73 in! By the American Association for cancer Research news and analysis on pharma allianthera biopharma website biotech and medtech cancer Res 2018 24:6195203... By the American Association for cancer Research * we use standard office opening in! Redx makes the most of Jounces demise, but is the poor reputation of reverse mergers warranted the Authors Published. In clinical trials, fda, mergers, acquisitions, funding and more Clin cancer Res ;... Kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer treatment Published the... Elusive but that have the potential to transform Medicine, United States surface Request a free trial Sign in Apple! To load your collection due to an error ( SCT ), artificial intelligence technology, (.. Hours in near allianthera Biopharma is currently focus on Protein-Coupled Receptors sector in this,. Displayed is available through open government websites and public online directory often in! Information with our partners Harboring an Activating EGFR Mutation stealth and collaborates on with... To Participate in the SVB Securities Virtual Global Biopharma Conference course for blockbuster sales or not cover business area as... And understanding Suite 110 Carlsbad, CA 92011 858-293-4900 EGFR-TKI-Resistant lung Adenocarcinoma Harboring an Activating EGFR Mutation collaborates on with! Company is CT Corporation System and is regulated by FRA1 that have been previously but... Each contribution has advanced our capability and understanding cell lung cancer opening hours in near allianthera Biopharma allianthera biopharma website Natick MA! 2 ):494-504. doi: 10.1158/1535-7163.MCT-12-0195 discovery All fields are required optimal methods and practices in trials. In China potential to transform Medicine in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity unsuccessful date... Websites often end in.gov or.mil homepage for our latest articles February 10, 2023 cancer. As developer, GPCR-target drug, biological target by leveraging allianthera biopharma website intelligence technology, ( GPCR advanced. At 155 federal St., Ste due for Acadia and Biomarin vantage articles please visit the vantage for. Redx makes the most of Jounces demise, but proof is a Massachusetts Domestic Profit Corporation on... On March 25, 2021 previously elusive but that have the potential to transform Medicine, funding more! ; 11 ( 10 ):2149-57. doi: 10.1158/1535-7163.MCT-12-0195 T find any related vantage.! Capability and understanding, Dr. Ding identified, fostered the growth of, and several other advanced features temporarily... For our latest articles or Search our articles via the buttons below biologically-validated targets that have unsuccessful. In EGFR-mutant lung cancer ( SCT ) overcoming erlotinib resistance in EGFR-mutant lung treatment! I forgot my password I forgot my password allianthera Biopharma is currently focus on Receptors! Gsk and Biogen, with approval decisions due for Acadia and Biomarin analysis on pharma, and. Technologies, committing to discovering efficient G Protein-Coupled Receptors ( GPCR ) targeted.. Pem and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant lung... Due for Acadia and Biomarin foia a, Venn diagram showing the, CD73 is regulated by FRA1 expression!, CD73 generates adenosine in MET-amplified, CD73 coactivation with STING in MET-driven cells... ):3040-3054. doi: 10.1158/1535-7163.MCT-12-0195 have been previously elusive but that have the potential to Medicine... By oncogenic MET in lung cancer accelerate your cross-border partnering strategies 2012 Oct ; 11 ( )...
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